Servicecore – Do not remove
Service Cores
Indiana CTSI Research Service Cores and Resources
IU Indianapolis
Behavioral Phenotyping Core (BPC)
The BPC advises upon and/or conducts behavioral experiments in rats or mice. Assays include assessments of general sensory and motor function, cognitive processing, affective reactivity, and PK/PD relationships in drug evaluations.
IU Indianapolis
Bioinformatics Core
The Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets.
Purdue University
Biological Evaluation (BE-SR)
The Biological Evaluation Shared Resource performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.
IU Indianapolis
Biospecimen Management Core (CTSL/SSF)
The CTSI Biospecimen Management Core consists of the Specimen Storage Facility (SSF) and the Clinical and Translational Support Laboratory (CTSL), which together offer cost efficient sample processing & storage services with a focus on consistent quality and sample integrity.
IU Indianapolis
Biostatistics and Health Data Science Core
The Biostatistics and Health Data Science Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.
Purdue University
Center for Comparative Translational Research
Translational research spans the continuum in which research findings from the researcher’s lab are moved to the patients ‘bedside’ (human) or ‘barn’ (animal). The Center for Comparative Translational Research (CTR) wants to make bridging the gap between benchtop and bedside/barn easier by helping researchers conduct comparative animal studies using induced and spontaneous disease models. It does so by facilitating, coordinating, integrating …
IU Indianapolis
Center for Medical Genomics (CMG)
The Center for Medical Genomics provides high-throughput genomics services including: genomic DNA sequencing, transcriptome RNA sequencing, miRNA sequencing, methylome or targeted methylation sequencing, protein DNA/RNA interaction (ChIP-seq, ATAC-seq and CLIP-seq), 10x single cell or single nuclei sequencing, and SNP genotyping.
IU Indianapolis
Chemical Genomics Core Facility
The CGCF is located in the Van Nuys Medical Science Building in Indianapolis. The core is equipped with five hoods for chemical synthesis, a microwave reactor, a parallel synthesizer and preparative HPLCs, LC-QTOF and 600 MHz NMR; a collection of 227,680 diversified small molecules, CRISPR libraries, liquid handling, assay detection and cell image systems.
Purdue University
Chemical Genomics Facility (CGF)
The Chemical Genomics Facility (CGF) provides affordable access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development and hit …
IU Indianapolis
Clinical Pharmacology Analytical Core (CPAC)
The Clinical Pharmacology Analytical core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.
IU Indianapolis
Genome Editing Center
The Indiana University Genome Editing Center (IUGEC) is a shared resource whose mission is to provide Indiana University and external investigators access to state-of-the-art genome editing technologies by assisting with the generation of genetically modified mouse models and cell lines in a time- and cost-effective manner.
IU Indianapolis
HANDS In Autism Interdisciplinary Training & Resource Center
The HANDS (Helping Answer Needs by Developing Specialists) in Autism® Interdisciplinary Training & Resource Center is located within the Department of Psychiatry at the Indiana University School of Medicine. The HANDS team offers services including:
(1) recruitment,
(2) behavioral, educational, functional, and/or vocational assessment of individuals across a broad range of ages and functioning levels, and
(3) program evaluation efforts targeted to a range …
IU Indianapolis
Histology and Histomorphometry Core (HHC)
Histology and Histomorphetry Core (HHC) provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility.
IU Bloomington
Imaging Research Facility (IRF)
The IRF is a state-of-the-art neuroimaging facility that enables cutting-edge neuroscience research and training using non-invasive imaging methodologies, including both MRI and EEG.
IU Indianapolis
In Vivo Therapeutics Core (IVT)
The In Vivo Therapeutics Core (IVTC) supports the research and development of safe and more efficacious drug treatment. The IVTC provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as a numerous in vivo pharmacology models to facilitate the development and testing of novel pharmacological & cellular therapies.
IU Indianapolis
In-Vivo Imaging Core
The In-Vivo Imaging Core provides imaging services for clinical trials, observational, and preclinical studies. We also provide radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities. Highly skilled faculty and staff are available to assist with research …
IU Indianapolis
Indiana Center for Biological Microscopy (ICBM)
The ICBM provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes (http://www.medicine.iupui.edu/ICBM/USING-THE-FACILITY). Center personnel train individual researchers to use all imaging systems and provide expert help in the design, conduct and analysis of imaging studies. As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking the necessary expertise.
IU Indianapolis
Infectious Diseases Laboratory (IDL)
The Infectious Diseases Laboratory (IDL) is skilled at performing clinical research studies including the evaluation of new molecular technologies for the diagnosis of a wide array of sexually transmitted pathogens, developing novel assays to meet the needs of individual research collaborators, and tailoring services to successfully meet study objectives. The laboratory has the capability to identify and type human papillomavirus (HPV) using molecular assays that can …
IU Indianapolis
Investigational Agent Acquisition Program
Goal: The goal of the CTSI Investigational Agent Acquisition Program (IAAP) is to assist CTSI investigators seeking investigational agents for use in clinical trials.
Scope: The IAAP program will assist in acquiring drugs, neutraceuticals, biologics or other materials to be used in a Investigational New Drug Application or IND-exempt clinical trial.
Eligibility: Any faculty within the CTSI member institutions.
Overview: Moving bench research into …
IU Indianapolis
IU School of Medicine Center for Electron Microscopy (iCEM)
The Indiana University School of Medicine Electron Microscopy Center is a full service research laboratory providing both Transmission and Scanning Electron Microscopy. The service provided can apply both traditional methods and recent technical developments to suit the investigator’s needs.
IU Indianapolis
Laboratory Animal Resource Center (LARC)
The Laboratory Animal Resource Center (LARC) provides basic husbandry, training, supplies, and specialized service support for medical research at IU School of Medicine.
IU Bloomington
Light Microscopy Imaging Center (LMIC)
The LMIC provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.
IU Bloomington
Macromolecular Crystallography Facility Integrated with the Crystallization Automation Facility (MCF/CAF)
The Macromolecular X-ray Crystallography Facility provides all resources for Crystal Screening and Optimization, Data Collection and Structure Determination of macromolecules.
Notre Dame
Mass Spectrometry and Proteomics Facility
Analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.
IU Bloomington
Mass Spectrometry Facility
The Indiana University Mass Spectrometry Facility (MSF) provides qualitative and quantitative small molecule mass spectrometry data. It also confirms chemical formulae of novel compounds by accurate mass spectrometry.
Notre Dame
Molecular Structure Facility
The Molecular Structure Facility at the University of Notre Dame provides for X-Ray structural studies of small (ca. 2kDa) molecules. The Facility has the capability to examine a wide range of molecules from “light atom” biologically relevant to metal-complexed compounds which can be readily analyzed using non-destructive techniques.
IU Bloomington
Oxidative Stress and Environmental Analysis Core
The Oxidative Stress Environmental Analysis Core laboratory has established a number of measurements for assessing oxidative stress and damage in a variety of biological samples with excellent accuracy and reproducibly using state of the art LC-MSMS, GC, and PCR equipment.
IU Bloomington
Physical and Biochemistry Instrumentation Facility (PBIF)
The PBIF provides resources to characterize particle properties as well as macromolecular interactions.
IU Indianapolis
Research Jam
Research Jam is an interdisciplinary team of healthcare, research, and design professionals. The team uses human-centered design research to collaborate with doctors, patients, and community members in an effort to ensure that health research, interventions, and communications are more relevant to the community they aim to serve. By engaging stakeholders in a co-design process, they are able to assist clients with recruitment strategies, study retention, and protocol …
Purdue University
Translational Pharmacology Facility
The PTP Core offers automated blood monitoring in rodents and large animals utilizing stress free sampling through CulexTM technology. We perform a host of services from early lead identification PK and PD assessment through product testing of human formulations in pigs and minipigs, including preclinical formulation development, biodistribution studies, metabolomics analysis, and in vivo toxicological evaluation.
Purdue University
Veterinary Clinical Trials (VCT)
The Veterinary Clinical Trials Support Service (VCT) facilitates veterinary clinical trials and provides expertise and technical support for translational clinical investigations using animal models of spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices.