Servicecore – Do not remove
Service Cores
Indiana CTSI Research Service Cores and Resources
IU Indianapolis
Behavioral Phenotyping Core (BPC)
The BPC advises upon and/or conducts behavioral experiments in rats or mice. Assays include assessments of general sensory and motor function, cognitive processing, affective reactivity, and PK/PD relationships in drug evaluations.
IU Indianapolis
Biochemical Genetics Laboratory
Our laboratory provides clinically validated liquid chromatography tandem mass spectrometry testing for researchers interested in quantifying metabolites in a wide range of biospecimens with a particular focus on amino acid, organic acid, and acylcarnitine analyses.
Purdue University
Biological Evaluation (BE-SR)
The Biological Evaluation Shared Resource performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.
Notre Dame
Biophysics Instrumentation Core (BIC) Facility
The BIC Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis.
IU Indianapolis
Biostatistics and Health Data Science Core
The Biostatistics and Health Data Science Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.
IU Indianapolis
Clinical Pharmacology Analytical Core (CPAC)
The Clinical Pharmacology Analytical core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.
IU Bloomington
Flow Cytometry Core Facility (FCCF)
The IU-B FCCF provides flow cytometry analysis, sorting and cell counting services, access to flow cytometry data analysis software, assistance with experimental design, and houses a mobile (on a cart) flow cytometry analyzer and a large particle sorter.
IU Indianapolis
Flow Cytometry Resource Facility (FCRF)
The Flow Cytometry Resource Facility (FCRF) provides flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.
IU Indianapolis
Histology and Histomorphometry Core (HHC)
Histology and Histomorphetry Core (HHC) provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility.
IU Indianapolis
Indiana Center for Biological Microscopy (ICBM)
The ICBM provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes (http://www.medicine.iupui.edu/ICBM/USING-THE-FACILITY). Center personnel train individual researchers to use all imaging systems and provide expert help in the design, conduct and analysis of imaging studies. As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking the necessary expertise.
IU Indianapolis
Infectious Diseases Laboratory (IDL)
The Infectious Diseases Laboratory (IDL) is skilled at performing clinical research studies including the evaluation of new molecular technologies for the diagnosis of a wide array of sexually transmitted pathogens, developing novel assays to meet the needs of individual research collaborators, and tailoring services to successfully meet study objectives. The laboratory has the capability to identify and type human papillomavirus (HPV) using molecular assays that can …
IU Indianapolis
Islet and Physiology Core
The Islet and Physiology Core of the Center for Diabetes and Metabolic Diseases provides investigators with the capability to obtain high quality rodent pancreatic islets for study. The Core also provides services for islet transplantation and will assist investigators who wish to perform immunohistochemistry, immunofluorescence, and/or analysis of beta cell mass on whole pancreata from mouse and rat models.
IU Bloomington
Laboratory Animal Resources (LAR)
LAR provides housing, food, water, bedding, enrichment and medical care for animals housed in LAR animal facilities to be used for research. Research is overseen by an Institutional Animal Care and Use Committee (IACUC) and the Institutional Official and is accredited by AAALAC International and their three primary standards (The Guide for the Care and Use of Laboratory Animals, Guide for the Care and Use of Agricultural Animals in Research and Teaching, and the European …
IU Bloomington
Laboratory for Biological Mass Spectrometry (LBMS)
The LBMS uses mass spectrometry to characterize proteins as well as other biologically-derived molecules. It specializes in the characterization of protein post-translational modifications, including glycosylation, phosphorylation, acetylation and persulfidation (S-sulfhydration). We also have an emphasis on identification of protein-interactions (including determination of protein-protein crosslinks) and quantitative comparisons of complex samples.
IU Bloomington
Macromolecular Crystallography Facility Integrated with the Crystallization Automation Facility (MCF/CAF)
The Macromolecular X-ray Crystallography Facility provides all resources for Crystal Screening and Optimization, Data Collection and Structure Determination of macromolecules.
Notre Dame
Mass Spectrometry and Proteomics Facility
Analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.
IU Bloomington
Mass Spectrometry Facility
The Indiana University Mass Spectrometry Facility (MSF) provides qualitative and quantitative small molecule mass spectrometry data. It also confirms chemical formulae of novel compounds by accurate mass spectrometry.
IU Bloomington
Physical and Biochemistry Instrumentation Facility (PBIF)
The PBIF provides resources to characterize particle properties as well as macromolecular interactions.
Purdue University
Pre-Clinical Research Laboratory (PCL)
The Pre-Clinical Research Laboratory (PCL) helps researchers conduct pre-clinical animal research by providing research expertise, technical support, surgical experience, and surgical facilities and equipment. The PCL is a multidisciplinary laboratory where researchers conduct advanced clinical and applied research using induced animal models ranging from rodents to pigs and sheep
Purdue University
Proteomics Facility
The Purdue Proteomics Facility provides chromatography, mass spectrometry and bioinformatic resources for the research communities on campus and beyond for protein characterization. These services include protein identification, relative and absolute quantitation, mapping post-translational modifications, and discovering new protein complexes and protein-protein interactions from a wide variety of sample types such as gel bands, cell or tissue lysates, and plasma or …
IU Indianapolis
3D Bioprinting Core (3DBPC)
We provide 3D bioprinting services with the Regenova Bio 3D Printer to generate tissue models (e.g., bone and liver) and we provide FABRICA bioreactor platforms to properly perfuse bioprinted tissue models with blood or cell culture media.
Purdue University
Veterinary Clinical Trials (VCT)
The Veterinary Clinical Trials Support Service (VCT) facilitates veterinary clinical trials and provides expertise and technical support for translational clinical investigations using animal models of spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices.