Service Cores

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Service Cores

Indiana CTSI Research Service Cores and Resources

The Indiana CTSI Research Service Cores and Resources are your aid to locate instrumentation and services suited to your research. A listing of a Core’s capabilities, contact information, and website address can be found by clicking their ‘Learn More’ button. All of the Designated Service Cores are eligible for CTSI Core Pilot grants and Post-Doc grants
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IU Indianapolis

Designated Service Core

Behavioral Phenotyping Core (BPC)

The BPC advises upon and/or conducts behavioral experiments in rats or mice. Assays include assessments of general sensory and motor function, cognitive processing, affective reactivity, and PK/PD relationships in drug evaluations.

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IU Indianapolis

Designated Service Core

Bioinformatics Core

The Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets.

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Purdue University

Non-Designated Service Resource

Bioinformatics Core

The Bioinformatics Core provides data analysis services for genomics, proteomics and metabolomics data.

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Notre Dame

Designated Service Core

Biophysics Instrumentation Core (BIC) Facility

The BIC Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis.

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IU Indianapolis

Designated Service Core

Biospecimen Collection and Banking Core

The IUSCCC Biospecimen Collection and Banking Core (BC2) provides an extensive collection of well-annotated samples from patients with malignancy and normal controls to support studies exploring the biologic basis of cancer, move basic findings to the clinic, and probe the biology underlying clinical and population phenomena. 

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IU Indianapolis

Designated Service Core

Biostatistics and Health Data Science Core

The Biostatistics and Health Data Science Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

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IU Indianapolis

Designated Service Core

Cellular Response Technologies Core

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

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IU Bloomington

Non-Designated Service Resource

Center for Evaluation, Policy, and Research (CEPR)

CEPR provides rigorous, high-quality, non-partisan evaluation, policy analyses, and research for meaningful, useful, and actionable data for clients and project stakeholders. Clients include international, federal and state agencies, public and private organizations, and foundations and endowments working across a range of fields and disciplines.

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IU Bloomington

Designated Service Core

Center for Genomics and Bioinformatics (CGB)

The CGB offers a wide range of genomic services, including high-throughput DNA/RNA extraction, library preparation, next-generation sequencing, and bioinformatic analysis.

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IU Indianapolis

Designated Service Core

Center for Medical Genomics (CMG)

The Center for Medical Genomics provides high-throughput genomics services including: genomic DNA sequencing, transcriptome RNA sequencing, miRNA sequencing, methylome or targeted methylation sequencing, protein DNA/RNA interaction (ChIP-seq, ATAC-seq and CLIP-seq), 10x single cell or single nuclei sequencing, and SNP genotyping.

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IU Bloomington

Designated Service Core

Center for Survey Research (CSR)

Leading academic research center providing expert research design, sampling, questionnaire design, interface development and programming, data collection, data processing, and analysis services for wide range of qualitative and quantitative research projects. Partnering on cutting-edge research that involves surveys, interviews, focus groups, or structured observations.

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Notre Dame

Non-Designated Service Resource

Center for Zebrafish Research

3,000 sq. ft. facility consisting of 8 double-sided racks and 38 single-sided racks, maintained independently. Separate room houses the nursery.

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Purdue University

Designated Service Core

Chemical Genomics Facility (CGF)

The Chemical Genomics Facility (CGF) provides affordable access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development and hit …

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IU Bloomington

Designated Service Core

Electron Microscopy Center (IUB-EMC)

The IU Bloomington Electron Microscopy Center (IUB-EMC) provides equipment, services and expertise for biological and material science electron microscopy.

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Purdue University

Designated Service Core

Flow Cytometry and Cell Sorting Facility

The Purdue Flow Cytometry Core Facility provides instrumentation, data analysis software, training and technical expertise for flow cytometry analysis and cell sorting. Our capabilities also include the characterization of genome and transcriptomes using the Fluidigm C1 and 10X Genomics systems, in partnership with the Purdue Genomics Core Facility.

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IU Bloomington

Designated Service Core

Flow Cytometry Core Facility (FCCF)

The IU-B FCCF provides flow cytometry analysis, sorting and cell counting services, access to flow cytometry data analysis software, assistance with experimental design, and houses a mobile (on a cart) flow cytometry analyzer and a large particle sorter.

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Notre Dame

Designated Service Core

Genomics and Bioinformatics Core Facility (GBCF)

The Genomics & Bioinformatics Core Facility (GBCF) at the University of Notre Dame offers comprehensive services and support for state-of-the-art genomics experiments and bioinformatics analysis. This includes next generation Illumina sequencing, a variety of standard and specialty DNA and RNA library construction methods, consultation, and analysis support.

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Purdue University

Designated Service Core

Genomics Facility

The Purdue Genomics Core provides both next generation – Illumina NovaSeq and MiSeq – and Sanger sequencing with an additional method to provide entire plasmid sequences for less than $35 via a service called “WideSeq”.

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IU Indianapolis

Non-Designated Service Resource

HANDS In Autism Interdisciplinary Training & Resource Center

The HANDS (Helping Answer Needs by Developing Specialists) in Autism® Interdisciplinary Training & Resource Center is located within the Department of Psychiatry at the Indiana University School of Medicine. The HANDS team offers services including:
(1) recruitment,
(2) behavioral, educational, functional, and/or vocational assessment of individuals across a broad range of ages and functioning levels, and
(3) program evaluation efforts targeted to a range …

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Purdue University

Designated Service Core

Imaging Facility

The Bioscience Imaging Facility, Purdue University, is a 24hr/7day access core facility specializing in confocal microscopy, multi-photon and light sheet microscopy, pre-clinical molecular and nuclear imaging and computed tomography (mCT) with offline analysis workstations.

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IU Bloomington

Designated Service Core

Imaging Research Facility (IRF)

The IRF is a state-of-the-art neuroimaging facility that enables cutting-edge neuroscience research and training using non-invasive imaging methodologies, including both MRI and EEG.

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IU Indianapolis

Designated Service Core

In-Vivo Imaging Core

The In-Vivo Imaging Core provides imaging services for clinical trials, observational, and preclinical studies. We also provide radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities. Highly skilled faculty and staff are available to assist with research …

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IU Indianapolis

Designated Service Core

Indiana Center for Biological Microscopy (ICBM)

The ICBM provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes (http://www.medicine.iupui.edu/ICBM/USING-THE-FACILITY).  Center personnel train individual researchers to use all imaging systems and provide expert help in the design, conduct and analysis of imaging studies.  As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking the necessary expertise.

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Notre Dame

Designated Service Core

Integrated Imaging Facility (NDIIF)

The Notre Dame Integrated Imaging Facility (NDIIF) is a state-of-the-art research core that makes available to the Notre Dame science and engineering community, as well as external customers, an integrated suite of sophisticated microscopes and imaging stations. The NDIIF also provides resident professional staff (three Ph.D.-level imaging specialists and two technicians) to guide the non-expert users. 

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IU Indianapolis

Non-Designated Service Resource

Investigational Agent Acquisition Program

Goal: The goal of the CTSI Investigational Agent Acquisition Program (IAAP) is to assist CTSI investigators seeking investigational agents for use in clinical trials.

Scope: The IAAP program will assist in acquiring drugs, neutraceuticals, biologics or other materials to be used in a Investigational New Drug Application or IND-exempt clinical trial.

Eligibility: Any faculty within the CTSI member institutions.

Overview: Moving bench research into …

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IU Indianapolis

Designated Service Core

Islet and Physiology Core

The Islet and Physiology Core of the Center for Diabetes and Metabolic Diseases provides investigators with the capability to obtain high quality rodent pancreatic islets for study.  The Core also provides services for islet transplantation and will assist investigators who wish to perform immunohistochemistry, immunofluorescence, and/or analysis of beta cell mass on whole pancreata from mouse and rat models. 

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IU Indianapolis

Designated Service Core

IU School of Medicine Center for Electron Microscopy (iCEM)

The Indiana University School of Medicine Electron Microscopy Center is a full service research laboratory providing both Transmission and Scanning Electron Microscopy. The service provided can apply both traditional methods and recent technical developments to suit the investigator’s needs.

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Purdue University

Non-Designated Service Resource

Life Science Microscopy Facility

The Life Science Microscopy Facility (LSMF) is an electron microscopy core with both service and individual use options.

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IU Bloomington

Designated Service Core

Light Microscopy Imaging Center (LMIC)

The LMIC provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.

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IU Bloomington

Designated Service Core

Macromolecular Crystallography Facility Integrated with the Crystallization Automation Facility (MCF/CAF)

The Macromolecular X-ray Crystallography Facility provides all resources for Crystal Screening and Optimization, Data Collection and Structure Determination of macromolecules.

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Notre Dame

Designated Service Core

Mass Spectrometry and Proteomics Facility

Analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.

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IU Indianapolis

Designated Service Core

Multiplex Analysis Core (MAC)

The Multiplex Analysis Core (MAC) offers microplate-based immunoassay systems that can perform multiplex analysis of multiple different analytes in a single sample. The MAC uses a Bio-Plex 200 Multiplex System with High Throughput Fluidics based on Luminex technology.

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IU Bloomington

Non-Designated Service Resource

Oxidative Stress and Environmental Analysis Core

The Oxidative Stress Environmental Analysis Core laboratory has established a number of measurements for assessing oxidative stress and damage in a variety of biological samples with excellent accuracy and reproducibly using state of the art LC-MSMS, GC, and PCR equipment.

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Purdue University

Non-Designated Service Resource

Pharmaceutical Manufacturing Core Facility

Pharmaceutical Manufacturing Core Facility provides support and capabilities for a wide range of research in pharmaceutical development and manufacturing. Technical support for the Facility is provided by the faculty of Industrial and Physical Pharmacy who have extensive pharmaceutical manufacturing experience in both industrial and academic environments.

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IU Bloomington

Non-Designated Service Resource

Physical and Biochemistry Instrumentation Facility (PBIF)

The PBIF provides resources to characterize particle properties as well as macromolecular interactions.

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Purdue University

Designated Service Core

Pre-Clinical Research Laboratory (PCL)

The Pre-Clinical Research Laboratory (PCL) helps researchers conduct pre-clinical animal research by providing research expertise, technical support, surgical experience, and surgical facilities and equipment. The PCL is a multidisciplinary laboratory where researchers conduct advanced clinical and applied research using induced animal models ranging from rodents to pigs and sheep

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Purdue University

Designated Service Core

Purdue MRI Facility

The Purdue MRI Facility houses two 3T full body MRI systems and one 7T small bore (animal) MRI system that are available for research involving MRI, MR spectroscopy, and other MR applications.

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IU Indianapolis

Designated Service Core

Regenstrief Data Services

Services RDS offerings include, but are not limited to:

• Feasibility
• DIY: i2b2
• Cohorts
• Recruitment Lists
• Registries
• Patient Lists
• Geocoding
• Phenotyping
• Deidentification
• EHR Integration/Innovation
• Application Development
• Application Prototypes
• Natural Language Processing (NLP)
• Data Linkage
• Machine Learning Models …

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IU Indianapolis

Non-Designated Service Resource

Research Jam

Research Jam is an interdisciplinary team of healthcare, research, and design professionals. The team uses human-centered design research to collaborate with doctors, patients, and community members in an effort to ensure that health research, interventions, and communications are more relevant to the community they aim to serve. By engaging stakeholders in a co-design process, they are able to assist clients with recruitment strategies, study retention, and protocol …

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IU Indianapolis

Non-Designated Service Resource

3D Bioprinting Core (3DBPC)

We provide 3D bioprinting services with the Regenova Bio 3D Printer to generate tissue models (e.g., bone and liver) and we provide FABRICA bioreactor platforms to properly perfuse bioprinted tissue models with blood or cell culture media.

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Purdue University

Designated Service Core

Transgenic and Genome Editing Facility (TGEF)

Offering transgenic and CRISPR-mediated targeted gene editing in mice and rats; gene-targeting in mouse embryonic stem cells (ES) cells; embryo and sperm cryopreservation; in vitro fertilization; rederivation for importation or clean-up of infected lines. Also offering assistance with project design and mouse/rat breeding colony maintenance.

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Purdue University

Non-Designated Service Resource

Veterinary Clinical Trials (VCT)

The Veterinary Clinical Trials Support Service (VCT) facilitates veterinary clinical trials and provides expertise and technical support for translational clinical investigations using animal models of spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices.

|2024-03-28T10:47:31-04:00March 28th, 2024|Comments Off on Service Cores

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