CTSI Translational Informatics Program
offers a range of technologies to help its investigators better
collaborate and carry out their translational research by facilitating
the easy sharing of information. The following is a (growing) list of
tools available to investigators through this site as well as
externally. For more information or to see examples, click on the tool
Prospective Patient Search and Cohort Discovery
de-identified patient query tool, an open-source web-based
tool provided by the Indiana CTSI and Regenstrief Institute to
investigators for de-identified clinical data queries with
minimal risk to patient privacy.
Additional resources for discovering and analyzing patient
data are provided by the
Regenstrief Data Core
Collaboration and File Sharing
Box (Indiana University):
Box is a no-cost cloud storage and collaboration environment
available to students, faculty, and staff at Indiana University
for sharing documents securely. For more information, see the
Box and other tools at Notre Dame available through the
Shared File Space
FileLocker at Purdue University
Research Data Sharing:
See REDCap below.
This program enables researchers to find scientists who are
conducting research in similar areas, or have useful complementary
expertise, whether at the IU School of Medicine or other
universities that participate in SciVal.
Data Capture & Management
(Research Electronic Data CAPture): REDCap is an easy-to-use
database management tool used to capture, use, and share
research data. It is also a tool to create, conduct, and manage
Thomson Reuters Services:
Thomson Reuters Services include access to MetaCoreTM, a pathway
analysis suite; MetaDrugTM, small molecule analysis tool; and
Eureka, a data-mining tool. Access is provided to investigators
at Indiana, Purdue and Notre Dame universities at a significantly
reduced rate through a
CTSI Thomson Reuters
GOBIOM Biomarkers Database:
GOBIOM is a comprehensive collection of all clinically evaluated
biomarkers associated with different therapeutic areas reported in
global clinical trials and preclinical markers in patients.
Access is free investigators at IU, Purdue and Notre Dame and
is supported by the Indiana CTSI Bioinformatics CORE and Indiana
Institute for Personalized Medicine.
Search & Discovery
Direct2Experts is a search tool which provides easy online access
to profile information on faculty researchers across the country.
The Indiana CTSI is one of 29 institutions in the CTSA Consortium
participating in the program.
GLAD4U is a free, web-based tool to help researchers answer such
questions as “Which genes are related to breast cancer?” GLAD4U
(Gene List Automatically Derived for You) automates the process
of creating gene lists. It makes use of the Entrez Programming
Utilities of the National Center for Biotechnology Information
(NCBI), a division of NLM.
NLMplus is a semantic search and knowledge discovery application
that simultaneously searches 59 NLM databases to allow users to
discover NLM’s rich content offerings in all areas of biomedicine
Quertle is an innovative website for searching and investigating
the biomedical literature. It is geared to active life science
professionals, including researchers and health care providers,
and is designed to save them considerable time and effort in
finding the literature they need. Quertle simultaneously searches
multiple sources of life science literature, including the
National Library of Medicine’s MEDLINE and TOXLINE.
For more information on these tools, as well as other useful topics,
Indiana CTSI Knowledge Base.
If you have questions or are interested in using one or more of these tools,