The Indiana CTSI Translational Informatics Program offers a range of technologies to help its investigators better collaborate and carry out their translational research by facilitating the easy sharing of information. The following is a (growing) list of tools available to investigators through this site as well as externally. For more information or to see examples, click on the tool title.

Prospective Patient Search and Cohort Discovery

  1. i2b2 de-identified patient query tool, an open-source web-based tool provided by the Indiana CTSI and Regenstrief Institute to investigators for de-identified clinical data queries with minimal risk to patient privacy.

    Additional resources for discovering and analyzing patient data are provided by the Regenstrief Data Core

Collaboration and File Sharing

  1. Box (Indiana University): Box is a no-cost cloud storage and collaboration environment available to students, faculty, and staff at Indiana University for sharing documents securely. For more information, see the FAQ.
  2. Box and other tools at Notre Dame available through the Shared File Space site.
  3. FileLocker at Purdue University PURR and FileLocker Purdue University
  4. Research Data Sharing: See REDCap below.
  5. SciValReSEARCH Connect: This program enables researchers to find scientists who are conducting research in similar areas, or have useful complementary expertise, whether at the IU School of Medicine or other universities that participate in SciVal.

Data Capture & Management

  1. REDCap (Research Electronic Data CAPture): REDCap is an easy-to-use database management tool used to capture, use, and share research data. It is also a tool to create, conduct, and manage online surveys.


  1. Thomson Reuters Services:  Thomson Reuters Services include access to MetaCoreTM, a pathway analysis suite; MetaDrugTM, small molecule analysis tool; and Eureka, a data-mining tool. Access is provided to investigators at Indiana, Purdue and Notre Dame universities at a significantly reduced rate through a  CTSI Thomson Reuters  agreement.

Biomedical Databases

  1. GOBIOM Biomarkers Database:  GOBIOM is a comprehensive collection of all clinically evaluated biomarkers associated with different therapeutic areas reported in global clinical trials and preclinical markers in patients. Access is free investigators at IU, Purdue and Notre Dame and is supported by the Indiana CTSI Bioinformatics CORE and Indiana Institute for Personalized Medicine.

Search & Discovery

  1. Direct2Experts:  Direct2Experts is a search tool which provides easy online access to profile information on faculty researchers across the country. The Indiana CTSI is one of 29 institutions in the CTSA Consortium participating in the program.
  2. GLAD4U:  GLAD4U is a free, web-based tool to help researchers answer such questions as “Which genes are related to breast cancer?” GLAD4U (Gene List Automatically Derived for You) automates the process of creating gene lists. It makes use of the Entrez Programming Utilities of the National Center for Biotechnology Information (NCBI), a division of NLM.
  3. NLMplus:  NLMplus is a semantic search and knowledge discovery application that simultaneously searches 59 NLM databases to allow users to discover NLM’s rich content offerings in all areas of biomedicine and health.
  4. Quertle:  Quertle is an innovative website for searching and investigating the biomedical literature. It is geared to active life science professionals, including researchers and health care providers, and is designed to save them considerable time and effort in finding the literature they need. Quertle simultaneously searches multiple sources of life science literature, including the National Library of Medicine’s MEDLINE and TOXLINE.


For more information on these tools, as well as other useful topics, visit the  Indiana CTSI Knowledge Base. If you have questions or are interested in using one or more of these tools, please contact