This page lists all Indiana CTSI funded proposals currently accepting applications. Clicking on the RFA title will provide you with further details for that mechanism. The “Click here to start a submission” link at the bottom of each RFA will take you to the CTSI grants system (which requires login) and allows you to start the application process. The “Return to your submission” link at the bottom of each RFA will take you to the CTSI grants system (which requires login) and allows you to return to an application that you have already started (once your account has been created if you are a new user).

The CTSI also has several resources to assist you as you plan your submission to any of the RFAs below:
  • CTSI designated Service Cores
  • Biostatistics, Epidemiology, and Research Design assistance
  • Project Development Teams


  • ALL OPEN RFAs


    Symposium, Workshop, and Conference Funding Program RFA

    SUBMISSION DEADLINE – OPEN

    The Indiana CTSI symposium, conference and workshop funding program is intended to facilitate sharing of ideas and findings in face-to-face discussion environments. The proposed symposium should include a translational research focus. The Indiana CTSI symposium program is specifically established to support presentation of new information to researchers in the Indiana CTSI that will establish research connections and lead to new research communication forums and ongoing collaborations. The application should describe how the proposed symposium will meet these goals.


    Submission Checklist


    1. Scientific symposia includes a translational component lead in part by full-time faculty (Assistant Professor/Scientist or above).
    2. Requested support does not exceed $1,500. Please note: funds are not available to cover refreshments or entertainment expenses.
    Contact Information: icreate@iu.edu / 317-278-2822

    Files for Investigators


    Click here to start a submission

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    Indiana Traumatic Spinal Cord and Brain Injury Research's Activity-Based Therapy Program

    SUBMISSION DEADLINE: October 29, 2018

    The overall objective of this program is to foster and encourage activity-based therapy programs for the prevention, treatment and cure of spinal cord and traumatic brain injuries, including acute management, medical complications, rehabilitative techniques, and neuronal recovery. The initiative for funding activity based therapy programs consists of two funding mechanisms:
  • 1) an RFA for programs providing rehabilitative clinical care and employing “activity based” approaches for traumatic spinal cord injury persons,
  • 2) an RFA for programs providing rehabilitative clinical care and employing “activity based” approaches for traumatic brain injury persons.


  • Applications for each RFA may be submitted for up to a maximum requested amount of $150,000 for the total duration of the project. Programs must be conducted in compliance with all state and federal laws.

    Contact Information: ICReATE icreate@iu.edu

    Files for Investigators


    Click here to start a submission

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    Digibiomarkers Technology Award

    SUBMISSION DEADLINE: November 12, 2018

    A new innovative application platform, DigiBiomarkers, has been developed by Indiana Biosciences Research Institute (IBRI) in collaboration with MavenSphere, Inc., to facilitate the rapid deployment of tools based on Apple’s ResearchKit, HealthKit, and CareKit software frameworks to capture digital information from individuals or patients.

    See Indiana CTSI news release: https://www.indianactsi.org/news_/new-mobile-research-tool-rfa/

    DigiBiomarkers (www.digibiomarkers) enables a wealth of data to be captured from patients which has not been available up to this point in time, and brings more objectivity and efficiency to clinical trials, thus accelerating the pace of quality research. The opportunity to remotely and continuously monitor patients provides a more contextually valid picture of patient health, while increasing the number of data points researchers have from which to draw conclusions.

    The Indiana CTSI is now offering access to this platform. Applications to this program are limited to a total of $10,000 for customization of the software. Duration of the project may vary, depending on the research needs.

    Researchers considering an application for use of this platform should contact Bharath Bynagari of DigiBiomarkers to discuss their project and receive a demonstration of the application platform prior to submission: bynagari@MavenSphere.com or 317-590-8275.

    RFA Contact Information: ICReATE / 317-278-2822 icreate@iu.edu

    Files for Investigators


    Click here to start a submission

    Click here to return to your submission

    Indiana Traumatic Spinal Cord & Brain Injury Research Grant

    SUBMISSION DEADLINE: December 10, 2018

    The overall objective of the Indiana Traumatic Spinal Cord & Brain Injury Research program is to foster and encourage research for the prevention, treatment and cure of spinal cord and traumatic brain injuries, including acute management, medical complications, rehabilitative techniques, and neuronal recovery. Collaborations are encouraged between Indiana-based researchers as well as with researchers located outside the state of Indiana, including researchers in other countries. Even though the Indiana statute encourages collaborations with researchers outside of Indiana, the primary research should be Indiana-based. Collaborations can be between Principal Investigators (PIs) at the same institution, different institutions, or a PI and a company. Salary support for collaborators outside of Indiana will be limited.

    Applications to this program are limited to a maximum requested amount of up to $80,000 per year for two years for basic science proposals and up to $100,000 per year for two years for proposals with research involving living human subjects.

    Contact Information:ICReATE Program: 317-278-2822 / icreate@iu.edu

    Files for Investigators


    Click here to start a submission

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    Young Investigator Award in Clinical-Translational Research (KL2)

    SUBMISSION DEADLINE: January 07, 2019

    The Indiana Clinical and Translational Sciences Institute (CTSI) is seeking applicants for the CTSI Young Investigator Awards in Clinical-Translational Research. These awards are designed to provide promising junior investigator faculty with the opportunity to be mentored in research-intensive multi-disciplinary settings toward the goal of developing careers in clinical-translational research. Clinical research includes epidemiological studies, clinical trials, or other investigations involving human subjects. Translational research consists of either “T1 research” (interface of basic science to human studies) or “T2 research” (interface of human studies to the community).

    To be eligible, candidates must fall into 1 of the following 2 categories:
    • Clinician-scientists with a doctoral degree (physicians, nurses, dentists, pharmacists, clinical psychologists, optometrists, veterinarians, allied health care professionals, etc.) or
    • Basic scientists with a PhD who are doing translational research, which involves some component of human subjects research and has high potential for early translation in impacting patient care.

    • Additional eligibility requirements are included in the full RFA Announcement and Application Instructions.

      Benefits include partial salary support, as well as tuition and fees for required and elective coursework, pilot research monies, and travel funds to attend the national CTSI young investigator meeting.

      Interested candidates must e-mail their CV to Patricia McGuire (pcmcguire@iu.edu) by December 19, 2018 for eligibility determination, prior to submission of a full application online.

      Contact Information: Patricia McGuire / 317-278-2824 pcmcguir@iu.edu

      Files for Investigators


      Click here to start a submission

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    CTSI Postdoctoral Training Awards in Translational Research (TL1)

    SUBMISSION DEADLINE: December 3, 2018

    The Indiana Clinical and Translational Sciences Institute (CTSI) is seeking applicants for special postdoctoral training awards in translational research. In biomedical terminology, translational research refers to what is popularly termed as “bench to bedside”; the process by which research in the lab translates into patient treatment. Translation may involve applying discoveries made during research (in the lab, through animal studies, etc.) to the development of clinical trials and studies in humans, or carrying out research aimed at enhancing the adoption of best practices, or both. To be eligible, candidates must have received a PhD or equivalent degree from an accredited domestic or foreign institution. Please refer to the competition guidelines for full eligibility criteria.

    Opportunities available for CTSI Postdoctoral Trainees include:

    CTSI Predoctoral Training in Translational Research (TL1)

    SUBMISSION DEADLINE: November 15, 2018

    The Indiana Clinical and Translational Sciences Institute (CTSI) is seeking applicants for special predoctoral training awards in translational research. In biomedical terminology translational research refers to what is popularly termed “bench to bedside”, the process by which research in the lab “translates” into patient treatment. Translation may involve applying discoveries made during research (in the lab, through animal studies, etc.) to the development of clinical trials and studies in humans, or carrying out research aimed at enhancing the adoption of best practices, or both.

    Funding is for two years (with the 2nd year of funding contingent upon satisfactory progress). Benefits include a stipend as well as health insurance and partial coverage of tuition and fees.

    Opportunities available for CTSI Pre-doctoral Trainees include:
    • Annual stipend comparable to other pre-doctoral training positions
    • Partial tuition and fees for coursework relevant to the applicant’s research
    • Mentoring with a faculty member whose research program includes peer reviewed, extramurally funded clinical or translational research
    • Networking with other pre and post-doctoral trainees, program mentors, and allied researchers from multiple institutions in Indiana to develop a cross-disciplinary community of scientists
    • Attendance at a national meeting that involves similar trainees from 40 other medical schools and research institutions
    • Funding is for one year and is renewable for one additional year based upon progress attained

    • Eligibility criteria for application include:

    Postdoc Challenge: Grant Funding to Utilize CTSI-Designated Core Facilities

    SUBMISSION DEADLINE: February 22, 2019

    The Indiana CTSI is soliciting proposals from postdoctoral researchers to develop translational research through the use of technologies and expertise at the Indiana CTSI-designated core facilities available at all partner institutions. Translational research refers to research in the lab that eventually translates into patient treatment to improve human healthcare. Translation involves applying discoveries made during research (in the lab, through animal studies, etc.) to the development of clinical trials and studies in humans.

    CTSI-designated core facilities are cores that undergo a yearly accreditation process through the Indiana CTSI for all partner institutions. The Postdoc Challenge offers postdoctoral researchers at Indiana University, Indiana University School of Medicine, IUPUI, Purdue University, and the University of Notre Dame valuable proposal writing and reviewing experience in areas related to translational research through the use of one or more of the CTSI-designated core facilities at any of the partner universities. This is a competitive opportunity for a $5,000 award in the form of an expense account for use of core facility services. Funding is to be used only for services provided by the core facilities. Indiana CTSI-designated core facilities are listed on the CTSI website. (https://www.indianactsi.org/servicecores)

    Applications to this program are limited to $5,000 and are of one (1) year duration.

    Informational Workshops Applicants are strongly encouraged to attend an Informational Workshop. Please download the flyer for your campus using the appropriate link below.

    Contact Information: Tommy Sors tsors@purdue.edu

    Files for Investigators


    Click here to start a submission

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    Global Health Research Pilot Project

    SUBMISSION DEADLINE: December 10, 2018

    The Indiana CTSI with the IU Center for Global Health is soliciting proposals from applicants developing or currently involved in collaborative global health research projects. The purpose of this RFA is to foster and encourage the development of new collaborative interdisciplinary research that seeks to identify innovations to address key global health challenges and improve health outcomes in resource limited settings. This RFA will fund pilot research projects with: (1) a high potential for attracting new extramural research funding; (2) a focus on strengthening collaborative multidisciplinary research collaborations between Indiana CTSI partner institutions (IU, Purdue, and Notre Dame) and key academic research centers abroad; and (3) demonstrate a high potential for reciprocal application to health challenges in Indiana as well as Low- and Middle-Income Country (LMIC) partner sites.

    This funding opportunity is open to investigators at Indiana CTSI partner institutions (IU, Purdue, and Notre Dame) and investigators at international institutions with existing cooperative relationships with an Indiana CTSI partner. Eligible proposals must be collaborative and include at least one co-principal investigator from an Indiana CTSI partner institution. Principal investigators/project directors must have the requisite skills, knowledge, time, and resources necessary to carry out the proposed research. This opportunity is open to individuals with full-time faculty appointments, graduate level trainees, and post-graduate fellows. Individuals who have received salary support or served as the principal investigator/project director for another Indiana CTSI global health pilot award under this funding mechanism from the Indiana CTSI in the 12 months prior to the submission deadline may not serve as the principal investigator/project director and cannot derive salary support.

    Contact Information: David Plater, Associate Director of Research, IU Center for Global Health dplater@iu.edu

    Files for Investigators


    Click here to start a submission

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    Global Health Reciprocal Innovation Awards

    SUBMISSION DEADLINE: December 10, 2018

    The Indiana CTSI with the IU Center for Global Health is soliciting proposals from applicants developing or currently involved in collaborative global health research projects. The purpose of this RFA is to foster and encourage reciprocal global health innovation among Indiana CTSI partner institutions (IU, Purdue, and Notre Dame) and their academic research partners abroad. This award will support the co-development and evaluation of high potential research to address critical health challenges in Indiana and/or at the CTSI ‘s LMIC partner sites globally. Special emphasis will be given to projects that address high priority needs, such as, reducing infant mortality and opioid addiction.

    Projects funded by this RFA will seek to develop demonstration projects and research to address critical global health challenges through reciprocal innovation with LMIC research partners. Research should focus on demonstrating innovations co-developed with LMIC and CTSI partners. These innovations should: (1) improve population health outcomes, particularly among women, children, and other vulnerable populations; (2) strengthen sustainable health care delivery systems; (3) address major disease burdens in low- to middle-income countries as well as Indiana; and (4) result in high impact innovations that provide reciprocal benefit to the communities Indiana CTSI institutions serve in at home and abroad. Innovations selected for demonstration will have been co-developed with at least one LMIC partner.

    Proposals should include plans to sustain and expand innovations that are demonstrated to be effective after the end of support from this RFA. This should include a detailed plan for scaling, funding, and integrating innovations into exiting systems or models of care. Additional preference will be given to projects that are likely to produce: (1) written products and publications (e.g., journal manuscripts, conference abstracts and presentations, evaluation reports, etc.); (2) fundable applications for extramural funding; (3) a beneficial long-term impact on an important health issue; and/or (4) result in the creation of intellectual property (IP).

    Contact Information: David Plater, Associate Director of Research, IU Center for Global Health dplater@iu.edu

    Files for Investigators


    Click here to start a submission

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    IU Grant Linking University Wide Expertise (GLUE) Award

    SUBMISSION DEADLINE: January 28, 2019

    The mission of the Grants Linking University–wide Expertise (GLUE) awards is to support “the planning and team building across campuses to develop of large multi-investigator and/or multi-project, milestone-driven, translational research teams who are planning to eventually submit a multi-year extramural grant applications with annual budgets of $300K or higher in direct costs per year”. Examples of such grants include (but are not limited to) PPGs, U series, multi PI R01s, STTRs and SPORE grants.

    Applications for GLUE grants are accepted for review at any stage of their development. It is expected that these planning/seed grants will increase multidisciplinary collaborations, institutional competitiveness, opportunities for extramurally funded training grants and overall institutional funding.

    The GLUE funding is available to collaborative teams where the lead PI of the research team is from IUB, and the other members of the team are from CTSI affiliate campuses. Applications are expected to have a maximum requested amount 100,000 per year for up to two (2) years.

    Contact Information: ICReATE / 317-278-2822 icreate@iu.edu

    Files for Investigators


    Click here to start a submission

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